Human growth hormone (HGH) therapy involves injections of synthetic HGH to treat medical conditions associated with growth hormone deficiency, such as short stature in children or lack of muscle mass in adults. HGH injections can help stimulate growth in children and adolescents who have unusually low levels of natural growth hormone. In adults, HGH therapy aims to replace diminished levels of the hormone, potentially building muscle mass or improving exercise capacity.
What conditions can HGH therapy treat?
HGH injections are FDA-approved to treat children with growth failure due to inadequate natural growth hormone. In adults, HGH therapy is approved to treat short bowel syndrome or muscle-wasting associated with HIV/AIDS. Off-label uses in adults aim to counteract supposed effects of aging like decreased muscle mass and bone density. However, effectiveness and safety for these uses remain questionable.
How is HGH therapy administered?
Synthetic growth hormone is injected under the skin, typically on a daily basis. The hormone must be refrigerated before use. Doses start low and gradually increase until achieving a personalized adequate level based on factors like age, weight, and treatment goals. Close medical supervision is vital to monitor potential side effects and adjust dosing if needed.
What are the risks or side effects?
Possible side effects include muscle and joint pain, swelling, high cholesterol, increased risk of diabetes, and enlarged hands, feet, or facial features. Rare but serious risks involve worsening heart disease, nerve and muscle damage, or increased cancer risk. Choosing an appropriate dose and monitoring via blood tests helps minimize adverse effects. Patients with health conditions like diabetes or cancer may not be candidates for HGH therapy.
Is HGH therapy results permanent?
Benefits of HGH therapy typically last only as long as treatment continues. Muscle mass and bone density often diminish after stopping injections. However, some studies show a subset of pediatric patients maintain normal height after completing childhood HGH therapy. Discuss expectations thoroughly with your health provider. Though tempting, unsupervised or long-term use of HGH poses substantial health dangers.
